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Jensen ON. Modification-specific proteomics: characterization of posttranslational modifications by mass spectrometry. Curr Opin Chem Biol. Valledor L, Jorrin J. Back to the basics: maximizing the information obtained by quantitative two dimensional gel electrophoresis analyses by an appropriate experimental design and statistical analyses. J Proteomics. Armirotti A, Damonte G. Achievements and perspectives of top-down proteomics.

Kosako H, Nagano K. Quantitative phosphoproteomics strategies for understanding protein kinase-mediated signal transduction pathways. Expert Rev Proteomics. Initial development and validation of a novel extraction method for quantitative mining of the formalin-fixed, paraffin-embedded tissue proteome for biomarker investigations. J Proteome Res. Solubilization of proteins from human lymph node tissue and twodimensional gel storage.

J Biochem Mol Biol. Isoelectric focusing in immobilized pH gradients: principle, methodology and some applications. J Biochem Biophys Methods. OFarrell PH. High resolution two-dimensional electrophoresis of proteins. J Biol Chem. The role of bioinformatics in two-dimensional gel electrophoresis. A systematic characterization of mitochondrial proteome from human T leukemia cells. Mol Cell Proteomics. Difference gel electrophoresis: a single gel method for detecting changes in protein extracts. Instruments and methods in proteomics.

Methods Mol Biol. MudPIT: A powerful proteomics tool for discovery. Discov Med. Large-scale analysis of the yeast proteome by multidimensional protein identification technology. Nat Biotechnol. Chen CH. Review of a current role of mass spectrometry for proteome research. Anal Chim Acta. Matrix-assisted laser desorption ionization mass spectrometry: applications in peptide and protein characterization. Protein Expr Purif. Mass Spectrom Rev. Int J Mol Sci.

Nguyen S, Fenn JB. Gas-phase ions of solute species from charged droplets of solutions. Wollnik H. Probability-based protein identification by searching sequence databases using mass spectrometry data. Electrophoresis ;20 18 An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database. Am Soc Mass Spectrom ;5 An introduction to quadrupoletime- of-flight mass spectrometry.

J Mass Spectrom ;36 8 The non-linear resonance ion trap. Part 2. A general theoretical analysis.

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The Orbitrap: a new mass spectrometer. J Mass Spectrom. Walther TC, Mann M. Mass spectrometry-based proteomics in cell biology. J Cell Biol. Quantitative analysis of complex protein mixtures using isotope-coded affinity tags. Anal Chem. Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Workflow comparison for label-free, quantitative secretome proteomics for cancer biomarker discovery: method evaluation, differential analysis, and verification in serum.

Comparison of label-free methods for quantifying human proteins by shotgun proteomics. Two-dimensional gel electrophoresis. Mass spectrometry-based proteomics in biomedical research: emerging technologies and future strategies. Expert Rev Mol Med. Phosphoproteomics identifies oncogenic Ras signaling targets and their involvement in lung adenocarcinomas. PLoS One. Lung cancer serum biomarker discovery using glycoprotein capture and liquid chromatography mass spectrometry. Mass spectrometry-based clinical proteomics: head-and-neck cancer biomarkers and drug-targets discovery.

Proteomic serum biomarkers and their potential application in cancer screening programs. Findeisen P, Neumaier M. Mass spectrometry based proteomics profiling as diagnostic tool in oncology: current status and future perspective. Clin Chem Lab Med. Fung ET. Clin Chem.

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Zhang Z, Chan DW. The road from discovery to clinical diagnostics: lessons learned from the first FDA-cleared in vitro diagnostic multivariate index assay of proteomic biomarkers. Cancer Epidemiol Biomarkers Prev. Targeted proteomic strategy for clinical biomarker discovery. Mol Oncol. Study of urinary proteomes in Anderson-Fabry disease. Ren Fail. Multiple sclerosis: Identification and clinical evaluation of novel CSF biomarkers.

Galectin-3 is a candidate biomarker for amyotrophic lateral sclerosis: discovery by a proteomics approach. Cerebrospinal fluid and plasma biomarkers in Alzheimer disease. Nat Rev Neurol. Ubiquitin as potential cerebrospinal fluid marker of Creutzfeldt-Jakob disease. Diagnostic cerebrospinal fluid biomarkers for Parkinsons disease: a pathogenetically based approach. Neurobiol Dis. High abundance synovial fluid proteome: distinct profiles in health and osteoarthritis.

Arthritis Res Ther. Proteomic analysis of the tear film in patients with keratoconus. Mol Vis ; Significant differences in nipple aspirate fluid protein expression between healthy women and those with breast cancer demonstrated by time-of-flight mass spectrometry. Breast Cancer Res Treat. Dawes C. Salivary flow patterns and the health of hard and soft oral tissues.

J Am Dent Assoc. In vitro remineralisation of eroded enamel lesions by saliva. J Dent.

Chapter 6: Personalized proteomics of human biofluids for clinical applications

Tabak LA. In defense of the oral cavity: the protective role of the salivary secretions. Pediatr Dent. Relationship between salivary flow rate and clinical symptoms and behaviours in patients with dry mouth. J Oral Rehabil. Aminotransferases and lactate dehydrogenase in saliva of diabetic patients. J Oral Pathol Med. Complexity of the human whole saliva proteome. J Physiol Biochem.

Sodium dodecyl sulphate-polyacrylamide gel electrophoresis of human parotid salivary proteins. Salivary proteins in rheumatoid arthritis and Sjogrens syndrome: one-dimensional and two-dimensional electrophoretic studies. HSP is present in human saliva. Med Sci Monit. Comparison of electrokinetics-based multidimensional separations coupled with electrospray ionization-tandem mass spectrometry for characterization of human salivary proteins. Mapping of proteins in human saliva using two-dimensional gel electrophoresis and peptide mass fingerprinting.

Discovery of oral fluid biomarkers for human oral cancer by mass spectrometry. Cancer Genomics Proteomics.

Proteomics of Human Body Fluids - Visith Thongboonkerd - Häftad () | Bokus

Salivary proteomics for oral cancer biomarker discovery. Clin Cancer Res. Differentially expressed protein markers in human submandibular and sublingual secretions. Int J Oncol. Huang CM. Comparative proteomic analysis of human whole saliva. Arch Oral Biol. Characterization of the human salivary basic proline-rich protein complex by a proteomic approach.

Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry. Ann NY Acad Sci. Evidence of autoantibodies to glutamic acid decarboxylase in oral fluid of type 1 diabetic patients. Diabetes Res Clin Pract. Identification of human whole saliva protein components using proteomics. Proteome analysis of glandular parotid and submandibular-sublingual saliva in comparison to whole human saliva by two-dimensional gel electrophoresis.

Two-dimensional liquid chromatography study of the human whole saliva proteome. A catalogue of human saliva proteins identified by free flow electrophoresis-based peptide separation and tandem mass spectrometry. Identification of protein components in human acquired enamel pellicle and whole saliva using novel proteomics approaches. Salivary Proteome Knowledge Base.

Sys-BodyFluid Database. Navazesh M. Methods for collecting saliva. Assessing the effects of diurnal variation on the composition of human parotid saliva: quantitative analysis of native peptides using iTRAQ reagents. Review: The physiology of saliva and transfer of drugs into saliva. Forensic Sci Int. Salivary estradiol and progesterone levels in conception and nonconception cycles in women: evaluation of a new assay for salivary estradiol. Fertil Steril. Salivary lead and cadmium in a young population residing in Mexico city.


Toxicol Lett. A newly developed PCR assay of H. Evidence of high prevalence of H. Dig Dis Sci. Cystatins S and C in human whole saliva and in glandular salivas in periodontal health and disease. J Dent Res. Immunoglobulins in the saliva of diabetic patients with periodontitis. Ann Dent. Salivary studies in cystic fibrosis.

Am J Dis Child. Sialochemistry for diagnosis of Sjogrens syndrome in xerostomic patients. Tissue peroxidase in the normal and neoplastic salivary gland. J Clin Lab Anal. Levels of glandular kallikrein in whole saliva obtained from patients with solid tumors remote from the oral cavity. The presence of soluble c-erbB-2 in saliva and serum among women with breast carcinoma: a preliminary study. Saliva and serum CA assays for detecting malignant ovarian tumors. Obstet Gynecol. Pre-analytic saliva processing affect proteomic results and biomarker screening of head and neck squamous carcinoma.

Analysis of the saliva proteome from patients with head and neck squamous cell carcinoma reveals differences in abundance levels of proteins associated with tumour progression and metastasis. Quantitative proteomics reveals myosin and actin as promising saliva biomarkers for distinguishing pre-malignant and malignant oral lesions. Potential biomarkers in saliva for oral squamous cell carcinoma. Oral Oncol. Biotechnological implications of the salivary proteome. Trends Biotechnol. Proteomic identification of salivary transferrin as a biomarker for early detection of oral cancer.

The transferrin receptor part I: biology and targeting with cytotoxic antibodies for the treatment of cancer. Clin Immunol. Salivary and serum proteomics in head and neck carcinomas: before and after surgery and radiotherapy. Cancer Biomark. Overview of the HUPO Plasma Proteome Project: results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of proteins and a publicly-available database.

On the development of plasma protein biomarkers. The human plasma proteome: history, character, and diagnostic prospects. Characterization of the low molecular weight human serum proteome. High-yield peptide-extraction method for the discovery of subnanomolar biomarkers from small serum samples. Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks. Full dynamic range proteome analysis of S. Quantitative, multiplexed assays for low abundance proteins in plasma by targeted mass spectrometry and stable isotope dilution.

Proteomic identification of human serum biomarkers in diabetes mellitus type 2.

J Pharm Biomed Anal. Proteomics-based identification of differentially-expressed proteins including galectin-1 in the blood plasma of type 2 diabetic patients. Multiplexed mass spectrometric immunoassay in biomarker research: a novel approach to the determination of a myocardial infarct. Buy eBook. Buy Hardcover. Buy Softcover. FAQ Policy. About this book The recent development of proteomics studies into clinical examinations of proteomics promises to lead toward the ultimate goals of earlier diagnosis, improved therapeutic outcome and successful prevention of diseases.

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